It depends on what year of truck you have. If it a 03 and up with the 6.0, you have a 5R110. That trans requires Mercon SP which is good for severe duty to about 60,000 miles. The older 4R100 transmissions only require merc/dex and should be changed every 15,000 to 25,000 miles. The same goes for the E4OD trans in the OBS trucks.