Quote of the week...
6.7s are a lot weaker on the bottom end than 6.0s and 6.4s... That's why you can push 800-900hp on a 6.4 before you even need to worry about the bottom end as long as you have pistons, studs, cam, etc...
The 6.7 is very capable but you will need to build the bottom end. That said, the heads and the valve train are a MUCH better design. I am still a little iffy on the transmissions, they don't see to hold up as well as the 5r110W at all. But that said, any time you start pushing 650-700hp you can expect a tranny rebuild.
Anything you will have to do to a duramax to make it reliable with true twins you will have to do with the 6.7psd. And turbo wise, if you are going that far all you need to do is contact vendors on here. Most know the right people to get you what you want be it tunes or hard parts. Our vendors and supporters here on the .org are a big reason why our community is the size it is.