I dont tow anything but I drive my truck hard. with the 6.0 and mods you wont feel the 35s. I dont know how the truck is when it was stock because it was modded then I lifted it after I put on my SCT and exhaust, intake, ect. But my mileage is down some. I would say im around 13-15 around town, maybe 17-18 on the highway? not really too sure. I would say if you want new tires get some 33s I had them on my old f250 and they were great. BFgoodrich tires 16 inch rims. Looked good and didnt need to lift the truck or anything, and that truck was a v10 and didnt notice any real mileage drop.
hope that help, im sure someone else will come on here and help out some more
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