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You can run 37's with a 4.5" lift if you stick with an 8.5-9" wide wheel with a 5.5" backspace you will be good up front. In the rear big 37's like Toyo's can still contact the back of the wheel well when the suspension compresses. If you go with the full leafs from Carli that will move the axle forward slightly. Also the 4.5" Pure kits have blocks that can move the axle forward a bit as well.:thumb: