321 makes a good point. The OEM parts for our trucks are going to be hard to beat in this case for durability, safety, and longevity. Powerstop, Hawk, EBC, etc. all sell premium aftermarket/upgrade parts like pads and rotors. All have been around a long time and, IMO, none are just crap. However, when it comes to the quality of the caliper, it will be hard to beat the OEM Ford stuff. Not only did Ford put them on our beloved Super Duty trucks but, if memory serves, they were also put on the 2nd Gen Lightning as well. Surely the rotors and pads were different for that application but just goes to show that a good design can go across multiple platforms from a manufacturing standpoint especially when it is used in a performance application as well as a heavy duty application. You want fancy red, blue, or black calipers? OK - paint them or pay the $ to have them powder coated. I like the slotted, cross-drilled, zinc washed rotors as much as the next guy from both an aesthetic as well as a heat and gas dissipating standpoint but does it really make that much of a difference in overall braking performance? IMO, I don't think it makes as much difference in stopping power as a good, strong caliper and Ford pretty much nailed that one right out of the gate. Of course, good pad selection means a lot, too. Brake dust, squeal, frictional coefficient, etc. are all factors for consideration. Speaking of which, you wrote that "It’s time to replace all my brakes and rotors". I'm assuming that you're referring to the calipers as well but you were not specific. Are the calipers bad? If not, then why would you change them? Pads and rotors are, of course, wear items and do need to be changed when worn out. Again, any of the above mentioned companies make parts that could be considered as an "upgrade over stock" but idk if the difference will be all that great.
above say the difference is indeed noticeable so there's the word from someone who actually has them. At any rate, good luck with your project. Like the old guy in said in Indiana Jones - The Last Crusade: "Choose, but choose wisely".