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I was in a similar boat last fall shopping for used super duty pickups. If you go with a 6.0L you will do studs if it hasn't been bulletproofed yet. If you purchase a 7.3L with the 4R100 automatic, you more than likely will be purchasing a new transmission in its lifetime if you tow heavy or add any power (my father in law has gone through 2 so far).
I chose the 6.0L because of the newer technology in the suspension, engine, charger, and transmission. Plus, it already had studs installed and egr delete. You can pick them up cheap for their reputation and throw a few thousand into the engine and still come out with a deal.
'06 F250 FX4 6.0L typical bolt on