I usually run mine to about 1/4 tank, then fill her up. I don't like letting her get below that, and I would add the additive before I filled her. As to the additive, everyone has their choice , mostly also based on budget. I usually get my additive from Walmart where I found it to be priced better.
I try to keep my tank full in the winter to limit condensation. I use Opti-lube XPD or Stanadyne, there's other good ones too, just make sure it's a demulsifier so the water will get trapped in the separator and not pass through the filters. Drain you separator once a month and put new Ford fuel filter in every other oil change and you should be good.
The demulsifier & a regular separator drain interval is critical on a common rail fuel system like a 6.4 or 6.7, they are expensive and they do not like water. There are enough horror stories of 6.7s with warranty denied for contaminated fuel that makes me content with my HEUI injection systems
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