Here's what happens, your Fuel Heater Element has rotted-out over the Summer. You haven't had it turned on yet and, now that it's cold, it got activated and is shorted. This blows that fuse (#22) and the PCM is also supplied by it so you don't start.
Here's what most people do about it,,,, Nothing
You probably don't ever need the Fuel Heater anyway (you don't live in Alaska do you?). Ford puts them in for the very Worst of conditions, stuff 99% of us don't ever see. So, if you're in the lower 48 of the US, you can just leave it unplugged.
You might also consider replacing it, I mean, Why Not???
. It's pretty easy to do, just next time you change the Filter you unscrew from the bottom of the bowl and put the new one in. - Up to you