I'm an IT Director that came up the ranks. I can and have removed that particular phish.
That particular rip off isn't actually a virus because your wife actually agreed to install it. Don't blame her, it's trickery phishing at its best. The anti-virus software that it say's it installs to clean up your system does nothing.
Now, consider this, how much money is that guy making off people.. It's a huge number.
Anyway, you have to delete the user profile then start the computer in safe mode and edit the registry to remove it from the run-once and default profile registry entries. Then before you restart the computer again you have to edit the default user profile itself and remove it from there.
Judging from your post, that's probably way beyond you. There is no antivirus program out there that can sucessfully remove it because it can't run until after it's already too late.
The guy that wrote it is good and believe it or not, it's technically not illegal.
The only other recourse is to rebuild the computer from scratch using the original CD's. You might be able to get the Geek Squad to fix it for you, I'm sure they've seen it before.
Or... Go on the internet on another computer, Google "remove 'blankity blank' antivirus".
I'd be willing to bet someone has an effective way of fixing this without resorting to wiping out the Windows partition.
In the future, store all, and I mean all important information on another partition or better yet another hard drive.
Even though a lot of people hate Norton Anti virus, they make some of the best removal tools for viruses as well as programs like this.
Check their website, if this program is as unwanted as I think, they may have a removal program as well as a procedure to follow to make sure that it is removed fully and permanently.
Did you try using System Restore and restoring it back to before the program was installed? Might work, right? What could it hurt?
You could also download (on another computer) SpybotSD as well as updates for it, burn to a CD, install on the laptop and run it. It might be worth a shot.
The people that write/update SpybotSD have been known to mark programs such as this as spyware.
If you have problems, PM me with the name of the program and I will see what I can find.