2001 7.3 low power, rough running, engine knock

[Supertruck]

I'm looking for some help. I've got a 2001 F-350 4x4 with a 7.3 that's equipped with a Banks Power Pack system, Six Gun Tuner, Ottomind chip, exhaust brake, trans-command (all Banks products), and an HTPS turbocharger.

I pull a 38' toyhauler 5th wheel trailer and it usually pulls it with no porblems. This weekend when I was hauling my trailer my exhaust temps were approximately 70 degrees higher than normal from the beginning on this trip. After about 1 1/2 hours on the road the truck lost power. I pulled off the hwy and the engine was running rough. I let the truck cool off a little and restarted the engine where there was no change in the rough running from idle to higher rpm. I needed to move the truck and after about 500' the engine developed a very loud knock. For safety reasons I couldn't stop and had to drive about a half mile with the engine knocking. The rough running went away but the knocking didn't. Engine oil pressure and the other guages were normal (except the exhaust temps.....about 70 degrees above normal). Exhaust smoke appeared to be a little more than normal. I replaced the fuel filter and decided to ease the truck back home. The truck seemed to run normal in terms of power but the EGT's were still high and the knock persisted. Then about 10 miles from home the knock mostly disappeared....still a faint knock at about 1800 rpm's.

I'm scratching my head about this one. Any suggestions?

[7004]

??

[thesmokinstroke02]

id first start with taking off the program and the chip. see if that helps. my tranny was shifting like it had a mind of its own and i took out the program then put it back in and it was fine.

[cchase]

I would check your valve cover harness, and maybe while your in there look at your push rods.

Do you have any codes?

[DJM]

Could be an Injector knock.

[ra17]

Hey powerstrokers, I'm kinda having the same problem, a fainting knocking starting @ 1800rpm then gets louder after 2500rpms. I can notice a vibration too. My engine has about 226,000 miles and I'm worried this more than just some injectors. Is it possible the injectors are out of time?