Knocking Not Sure If Fuel Or Motor Help Please

[Bamcquirt1]

Went to the Lucus oil jambo in Lima Ohio this past weekend drove in the cruise line all day Saturday an headed home Sunday afternoon. Half way for
Columbus started knocking an slowed down to 55. Pulled in rest area an idled fine. Got out no visible leaks anywhere. Let sit for 15 minutes started back up then was knocking an running ruff at idle took off out of rest area didn't get a mile down the road an shut off. Towed it home went out today an started but still knocking an running ruff. Pump under driver door is coming on. Need opinions on what could be the problem. How could I know if I dropped an injector or what else could it be. Thanks guys sorry so long just wanted to inform exactly what happened. Anything would help !

[flogvul]

When is last time replaced fuel filter? Look at simple things first. Air filter clean? Oil good or need changed. Open fuel water seperator on side of fuel bowl. Is fuel pump actually pumping fuel into bowl? Any smoke? Color? Do you have any codes or service engine light soon on? Run bio fuel?