I have the AirDog2 adjustable fuel pump.
I think the two most important reasons to use it are, it removes the air bubbles and vapor from the fuel, injectors don't like to run dry or intermittent.
And also it keeps the pressure high under hard accelleration, and big tunes. It's all about pressure.
I guess injectors # 7 and 8 are the last to get fuel under a good romp on the skinny pedal. These trucks require a constant 60-70 psi to injectors.
This is a regulated pump, so no need to buy regulated return kit.
It also makes emptying the fuel/water seperator, and changing the primary fuel filter way easier to change.
The air dog2 doesn't require you to drop the fuel tank. But the standard instructions say to re-use the HFCM (stock pump module) for the return of unused fuel to tank. There are better ways, such as deleting HFCM all together, there are posts about this, search on...
Good Luck !