Injector Noise and difference when pluged in

[Whiskey River]

Now that the temps are dropping have some injector questions. 06 6.0 w/225K miles, was a one owner truck but not sure if original injectors or not. When cold 1st 2 minutes it runs sounds like the rods are going to come through the block I mean it really raises heck, if plugged in it's quite as a mouse. Same thing in warmer months if it's really warm no noise the colder it gets the louder they get. My question; is this normal for injectors with high mileage? Or is there other possibilities for my noise that isn't injectors?
Thanks

[Whiskey River]

No one can tell me if the block heater being plugged in and the block warm would contribute to the injectors being quite? Versus when it's 30 degrees and not plugged in they raise heck. Thanks