There is nothing that you "have" to do to your tranny, however... it is very wise to at least put a temp gauge on it since they tend to overheat quick with any after market tuning. Depending on how serious you want to take it and also what you are doing with your truck you may also want to consider having a lager oil cooler put in and possibly a shift kit if you haul a lot. However, if you are just after a little better fuel mileage or some pep when you go to pass people, you don't need to stress it too much.