I ordered the Audiophile system with integrated Sirius radio and am very happy with the end result. Audio quality is excellent the the Sirius reception/quality is much better that the stand alone Sirius sytem that transmits through an FM tuner that is in my wife's car. The Sirius display is small and can't be manipulated via the steering wheel (I don't have the navigation system) but it's only a small setback since you can program 18 preset stations. The subwoofer does plug into the wiring harness behind the back seat and produces excellent bass.
The delivery of my truck was delayed almost two weeks because Ford is in a backorder status for the Sirius radio. I've had my F250 Crew Cab FX4 for three weeks now and couldn't be happier.