It's not hard to twist off of stud on a SD...I did that last year on one of our DRWs as I didn't catch that the thread on the stud got damaged.
I did see pics of a truck with lug-centric wheels that had some lugs snap, and pulled some studs through the hub itself....and I think some lug nuts were gone. Which happened first and what was the cause, who knows. It was towing a 14k gooseneck coming on a steep decline if I remember correctly.
Personally I can't say that I've seen any issues, and we sell a lot of lug-centric wheels as that is what the majority of all wheels are for the Super Duty.
Myself, I do run Weld wheels on both my SDs as Welds are hub-centric. And they are one piece forged which I also like